Novel prostate cancer susceptibility gene SP6 predisposes patients to aggressive disease
نویسندگان
چکیده
منابع مشابه
Genetic susceptibility to aggressive prostate cancer.
In 2006, f234,460 men in the U.S. will be diagnosed with prostate cancer, and >27,000 deaths will be attributed to the disease (1). There is substantial phenotypic variability among cases and the disease incidence varies by age, race, and family history. In the U.S., f70% of all cases are z65 years at diagnosis, and the median age at diagnosis is 68 years (2). Several types of epidemiologic stu...
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Autopsy studies suggest that most aging men will develop lesions that, if detected clinically, would be diagnosed as prostate cancer (PCa). Most of these cancers are indolent and remain localized; however, a subset of PCa is aggressive and accounts for more than 27,000 deaths in the United States annually. Identification of factors specifically associated with risk for more aggressive PCa is ur...
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BACKGROUND Although a rapidly growing number of candidate biological markers of prognosis and/or response to specific treatments in prostate cancer, none have to date showed ability to completely prognosticate prostate cancer on evidence based urology. OBJECTIVE To review the pertinent literature on the issue. ACQUISITION OF EVIDENCE A comprehensive review of the current literature was done...
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ژورنال
عنوان ژورنال: Prostate Cancer and Prostatic Diseases
سال: 2021
ISSN: 1365-7852,1476-5608
DOI: 10.1038/s41391-021-00378-5